c-Jun Controls the Ability of IL-12 to Induce IL-10 Production from Human Memory CD4+ T Cells
نویسندگان
چکیده
منابع مشابه
c-jun controls the ability of IL-12 to induce IL-10 production from human memory CD4+ T cells.
IL-12p70 is an immunoregulatory cytokine that has been shown to induce IL-10 production from CD4+ T cells, yet the underlying cellular mechanisms controlling this process are poorly understood. In the present study, we demonstrate that IL-12p70 induces IL-10 production from human memory CD4+ T cells via a PI3K-dependent signaling mechanism. Specifically, stimulation of human memory CD4+ T cells...
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ژورنال
عنوان ژورنال: The Journal of Immunology
سال: 2009
ISSN: 0022-1767,1550-6606
DOI: 10.4049/jimmunol.0901283